Science
- All of our products are based in research, and decision making is based on both a philosophy and psychological research. Therefore, it is appropriate to keep up with the latest research to get a deeper understanding.
- If old world wisdom can only get us so far, applying more of that and spreading it in more ways is not going to help. Many self help books and gurus try this recycled wisdom.
- Previous research can only go so far, as it tends to not cross the boundaries.
- We took a different approach by combining psychology, philosophy, social sciences and biology and medicine to look at the broader picture of what is going on with ourselves.
- Such an approach will not be tried in the research community, as it is too broad and sits between multiple disciplines. But we don't have such limitations.
General
- Freeman, A. (2026). Mind It! For Health & Happiness [Unpublished manuscript].
Decision
- Baumeister, R. F., Bratslavsky, E., Finkenauer, C., & Vohs, K. D. (2001). Bad is stronger than good. Review of General Psychology, 5(4), 323–370. https://doi.org/10.1037/1089-2680.5.4.323
- Cole, S. A., Sannidhi, D., Jadotte, Y. T., & Rozanski, A. (2023). Using motivational interviewing and brief action planning for adopting and maintaining positive health behaviors. Progress in Cardiovascular Diseases, 77, 86–94.
- Miller, W. R., & Rollnick, S. (2012). Motivational interviewing: Helping people change. Guilford Press.
- Mediating role of impaired wisdom. (2022).
- Nawijn, J. (n.d.). Leisure travel and happiness [Doctoral dissertation].
- Neurolinguistic programming and health outcomes. (n.d.).
Self
- Freeman, A. (2026). Mind It! For Health & Happiness [Unpublished manuscript].
- Brown, K. W., & Ryan, R. M. (2003). The benefits of being present: Mindfulness and its role in psychological well-being. Journal of Personality and Social Psychology, 84(4), 822–848.
- Christianto, V., & Smarandache, F. (2020). A review on how an ancient forgiveness way called Ho’oponopono can boost human health and immune system. EC Neurology, 12(6), 64–69.
- Hassed, C., & Chambers, R. (2014). Mindful learning: Reduce stress and improve brain performance for effective learning (Vol. 3). Exisle Publishing.
- Ishii, T., Taweesedt, P. T., Chick, C. F., O’Hara, R., & Kawai, M. (2024). From macro to micro: Slow-wave sleep and its pivotal health implications. Frontiers in Sleep, 3, 1322995.
- Ito, K. L. (n.d.). Ho’oponopono, “to make right”: Hawaiian conflict resolution and metaphor in the construction of a family therapy.
- Loama, R. T., & Suwarjo. (2025). Hidden wounds of the inner child: A systematic review on the psychological effects of childhood trauma in adulthood. Indonesian Journal of Counseling and Development, 7(2), 210–224. https://doi.org/10.32939/ijcd.v7i2.6088
- McManus, E., Haroon, H., Duncan, N. W., Elliott, R., & Muhlert, N. (2022). The effects of stress across the lifespan on the brain, cognition and mental health: A UK Biobank study. Neurobiology of Stress, 18, 100447.
- Rogers, D. (n.d.). Dark shadow: Examining the inner critic and shame [Doctoral dissertation, Pacifica Graduate Institute].
- Thakurdas, A. (2008). Ho’oponopono: Universal healing method for mankind. 8(3).
- Vago, D. R., & Zeidan, F. (2016). The brain on silent: Mind wandering, mindful awareness, and states of mental tranquility. Annals of the New York Academy of Sciences, 1373(1), 96–113.
- Wall, J. A., Jr., & Callister, R. R. (1995). Ho’oponopono: Some lessons from Hawaiian mediation. Negotiation Journal, 11(1), 45–54.
- Xin, Z., Li, S., Jia, Y., & Yuan, H. (n.d.). Analysis of self-healing of depression by helping others in adolescents from the perspective of constructivism. Frontiers in Psychiatry.
- Zhang, J., Wu, Z., Tao, H., Chen, M., Yu, M., Zhou, L., Sun, M., Lv, D., Cui, G., Yi, Q., Tang, H., An, C., Liu, Z., Huang, X., & Long, Y. (n.d.). Profile and mental health characterization of childhood overprotection/overcontrol experiences among Chinese university students: A nationwide survey. Frontiers in Psychiatry.
Connect
- Burkett, J. P., & Young, L. J. (n.d.). The behavioral, anatomical and pharmacological parallels between social attachment, love and addiction.
- Carter, C. S., & Kingsbury, M. A. (2022). Oxytocin and oxygen: The evolution of a solution to the “stress of life.” Philosophical Transactions of the Royal Society B: Biological Sciences, 377, 20210054. https://doi.org/10.1098/rstb.2021.0054
- Carter, C. S., & Perkeybile, A. M. (n.d.). The monogamy paradox: What do love and sex have to do with it?
- Dölen, G., Darvishzadeh, A., Huang, K. W., & Malenka, R. C. (n.d.). Social reward requires coordinated activity of accumbens oxytocin and 5-HT.
- Gettler, L. T., Sarma, M. S., Lew-Levy, S., Bond, A., Trumble, B. C., & Boyette, A. H. (2019). Mothers’ and fathers’ joint profiles for testosterone and oxytocin in a small-scale fishing-farming community: Variation based on marital conflict and paternal contributions. Brain and Behavior, 9, e01367. https://doi.org/10.1002/brb3.1367
- Goldstein, T. R., & Bloom, P. (n.d.). The mind on stage: Why cognitive scientists should study acting. Trends in Cognitive Sciences.
- Goldstein, T. R., & Winner, E. (2012). Enhancing empathy and theory of mind. Journal of Cognition and Development. https://doi.org/10.1080/15248372.2011.573514
- Gu, R., Huang, W., Camilleri, J., Xu, P., Wei, P., Eickhoff, S. B., & Feng, C. (n.d.). Love is analogous to money in human brain: Coordinate-based and functional connectivity meta-analyses of social and monetary reward anticipation.
- Hirsch, J. L., & Clark, M. S. (2019). Multiple paths to belonging that we should study together. Perspectives on Psychological Science, 14(2), 238–255. https://doi.org/10.1177/1745691618803629
- Holt-Lunstad, J. (2018). Why social relationships are important for physical health: A systems approach to understanding and modifying risk and protection. Annual Review of Psychology, 69, 437–458. https://doi.org/10.1146/annurev-psych-122216-011902
- Holt-Lunstad, J., Smith, T. B., & Layton, J. B. (2010). Social relationships and mortality risk: A meta-analytic review. PLoS Medicine, 7(7), e1000316.
- Kemp, A. H., Arias, J. A., & Fisher, Z. (2017). Social ties, health and wellbeing: A literature review and model. In Neuroscience and social science: The missing link (pp. 397–427).
- Mandryk, R. L., Frommel, J., Armstrong, A., & Johnson, D. (2020). How passion for playing World of Warcraft predicts in-game social capital, loneliness, and wellbeing. Frontiers in Psychology, 11, 2165. https://doi.org/10.3389/fpsyg.2020.02165
- Paletta, P., Bass, N., Kavaliers, M., & Choleris, E. (2022). The role of oxytocin in shaping complex social behaviours: Possible interactions with other neuromodulators. Philosophical Transactions of the Royal Society B: Biological Sciences, 377, 20210058. https://doi.org/10.1098/rstb.2021.0058
- Bowling, D. L., Gahr, J., Graf Ancochea, P., Hoeschele, M., Canoine, V., Fusani, L., & Fitch, W. T. (n.d.). Endogenous oxytocin, cortisol, and testosterone in response to group singing.
- Barlett, C. P., & Rodeheffer, C. (2009). Effects of realism on extended violent and nonviolent video game play on aggressive thoughts, feelings, and physiological arousal. Aggressive Behavior, 35, 213–224.
Biology and Medicine
- Anderson, G. (2023). A more holistic perspective of Alzheimer’s disease: Roles of gut microbiome, adipocytes, HPA axis, melatonergic pathway and astrocyte mitochondria in the emergence of autoimmunity. Frontiers in Bioscience–Landmark, 28(12), 355. https://doi.org/10.31083/j.fbl2812355
- Andrews, P., & Johnson, R. J. (2020). Evolutionary basis for the human diet: Consequences for human health. Journal of Internal Medicine, 287, 226–237. https://doi.org/10.1111/joim.13011
- Borroni, D., Mazzotta, C., Rocha-de-Lossada, C., Sánchez-González, J.-M., Ballesteros-Sanchez, A., García-Lorente, M., Zamorano-Martín, F., Spinelli, A., Schiano-Lomoriello, D., & Tedesco, G. R. (2023). Dry eye para-inflammation treatment: Evaluation of a novel tear substitute containing hyaluronic acid and low-dose hydrocortisone. Biomedicines, 11, 3277. https://doi.org/10.3390/biomedicines11123277
- Bradbury, J. (2011). Docosahexaenoic acid (DHA): An ancient nutrient for the modern human brain. Nutrients, 3, 529–554. https://doi.org/10.3390/nu3050529
- Briones, A., Gagno, S., Martisova, E., Dobarro, M., Aisa, B., Solas, M., Tordera, R., & Ramírez, M. J. (2011). Stress-induced anhedonia is associated with an increase in Alzheimer’s disease-related markers. British Journal of Pharmacology.
- Caslin, B., Mohler, K., Thiagarajan, S., & Melamed, E. (2021). Alcohol as friend or foe in autoimmune diseases: A role for gut microbiome? Gut Microbes, 13(1), 1916278. https://doi.org/10.1080/19490976.2021.1916278
- Choubey, A., Girdhar, K., Kar, A. K., Kushwaha, S., Yadav, M. K., Ghosh, D., & Mondal, P. (2020). Low-dose naltrexone rescues inflammation and insulin resistance associated with hyperinsulinemia. Journal of Biological Chemistry.
- Colcott, J., Guerin, A. A., Carter, O., Meikle, S., & Bedi, G. (2024). Side-effects of MDMA-assisted psychotherapy: A systematic review and meta-analysis.
- Cuevas-Cervera, M., Perez-Montilla, J. J., Gonzalez-Muñoz, A., Garcia-Rios, M. C., & Navarro-Ledesma, S. (2022). The effectiveness of intermittent fasting, time restricted feeding, caloric restriction, a ketogenic diet and the Mediterranean diet as part of the treatment plan to improve health and chronic musculoskeletal pain: A systematic review. International Journal of Environmental Research and Public Health, 19, 6698. https://doi.org/10.3390/ijerph19116698
- Dai, S., Wei, J., Zhang, H., Luo, P., Yang, Y., Jiang, X., Fei, Z., Liang, W., Jiang, J., & Li, X. (2022). Intermittent fasting reduces neuroinflammation in intracerebral hemorrhage through the Sirt3/Nrf2/HO-1 pathway. Journal of Neuroinflammation, 19, 122. https://doi.org/10.1186/s12974-022-02474-2
- Dai, Z., Zhang, H., Wu, F., Chen, Y., Yang, C., Wang, H., Sui, X., Guo, Y., Xin, B., Guo, Z., et al. (2022). Effects of 10-day complete fasting on physiological homeostasis, nutrition and health markers in male adults. Nutrients, 14, 3860. https://doi.org/10.3390/nu14183860
- Dai, Z., Zhang, H., Sui, X., Wu, F., Zhang, C., Fan, Z., Wang, H., Guo, Y., Yang, C., Jiang, S., Wang, L., Xin, B., & Li, Y. (n.d.). Analysis of physiological and biochemical changes and metabolic shifts during 21-day fasting hypometabolism.
- de Wit, H., Molla, H. M., Bershad, A., Bremmer, M., & Lee, R. (n.d.). Repeated low doses of LSD in healthy adults: A placebo-controlled, dose-response study.
- Dynka, D., Paziewska, A., & Kowalcze, K. (2023). Keto menu—Effect of ketogenic menu and intermittent fasting on the biochemical markers and body composition in a physically active man—A controlled case study. Foods, 12, 3219. https://doi.org/10.3390/foods12173219
- Fazeli, P. K., Zhang, Y., O’Keefe, J., Pesaresi, T., Lun, M., Lawney, B., & Steinhauser, M. L. (n.d.). Prolonged fasting drives a program of metabolic inflammation in human adipose tissue.
- Fiolet, A. T. L., Lin, A., Kwiecinski, J., Tutein Nolthenius, J., McElhinney, P., Grodecki, K., et al. (n.d.). Effect of low-dose colchicine on pericoronary inflammation and coronary plaque composition in chronic coronary disease: A sub-analysis of the LoDoCo2 trial.
- GBD 2016 Alcohol Collaborators. (2018). Alcohol use and burden for 195 countries and territories, 1990–2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet, 392, 1015–1035.
- González Olmo, B. M., Butler, M. J., & Barrientos, R. M. (2021). Evolution of the human diet and its impact on gut microbiota, immune responses, and brain health. Nutrients, 13, 196. https://doi.org/10.3390/nu13010196
- Hutten, N. R. P. W., Mason, N. L., Dolder, P. C., Theunissen, E. L., Holze, F., Liechti, M. E., Feilding, A., Ramaekers, J. G., & Kuypers, K. P. C. (2020). Mood and cognition after administration of low LSD doses in healthy volunteers: A placebo-controlled dose-effect finding study. European Neuropsychopharmacology, 41, 81–91.
- Jordan, S., Tung, N., Casanova-Acebes, M., et al. (n.d.). Dietary intake regulates the circulating inflammatory monocyte pool.
- Justice, N. J. (n.d.). The relationship between stress and Alzheimer’s disease. Neurobiology of Stress.
- Khan, H., Ullah, H., Aschner, M., Cheang, W. S., & Akkol, E. K. (n.d.). Neuroprotective effects of quercetin in Alzheimer’s disease. Biomolecules.
- Knezevic, E., Nenic, K., Milanovic, V., & Knezevic, N. N. (2023). The role of cortisol in chronic stress, neurodegenerative diseases, and psychological disorders. Cells, 12, 2726. https://doi.org/10.3390/cells12232726
- Kupka, E., Hesselman, S., Hastie, R., Lomartire, R., Wikström, A. K., & Bergman, L. (n.d.). Low-dose aspirin use in pregnancy and the risk of preterm birth: A Swedish register-based cohort study.
- Lambadiari, V., Katsimbri, P., Kountouri, A., Korakas, E., Papathanasi, A., Maratou, E., Pavlidis, G., Pliouta, L., Ikonomidis, I., Malisova, S., et al. (2024). The effect of a ketogenic diet versus Mediterranean diet on clinical and biochemical markers of inflammation in patients with obesity and psoriatic arthritis: A randomized crossover trial. International Journal of Molecular Sciences, 25, 2475. https://doi.org/10.3390/ijms25052475
- Lambert, B. S., Miller, K. E., Delgado, D. A., Chaliki, K., Lee, J., Bauza, G., Taraballi, F., Dong, D., Tasciotti, E., Harris, J. D., & McCulloch, P. C. (2020). Acute physiologic effects of performing yoga in the heat on energy expenditure, range of motion, and inflammatory biomarkers. International Journal of Exercise Science, 13(3), 802–817.
- Leggieri, M., Thaut, M. H., Fornazzari, L., Schweizer, T. A., Barfett, J., Munoz, D. G., & Fischer, C. E. (2019). Music intervention approaches for Alzheimer’s disease: A review of the literature. Frontiers in Neuroscience, 13, 132. https://doi.org/10.3389/fnins.2019.00132
- Lesmana, R., Yusuf, I. F., Goenawan, H., Achadiyani, Khairani, A. F., Fatimah, S. N., & Supratman, U. (2020). Low dose of β-carotene regulates inflammation, reduces caspase signaling, and correlates with autophagy activation in cardiomyoblast cell lines.
- Lundberg, P., Abrahamsson, A., Kihlberg, J., Tellman, J., Tomkeviciene, I., Karlsson, A., Kristoffersen Wiberg, M., Warntjes, M., & Dabrosin, C. (2024). Low-dose acetylsalicylic acid reduces local inflammation and tissue perfusion in dense breast tissue in postmenopausal women. Breast Cancer Research, 26, 22. https://doi.org/10.1186/s13058-024-01780-2
- Mattson, M. P., Moehl, K., Ghena, N., Schmaedick, M., & Cheng, A. (2018). Intermittent metabolic switching, neuroplasticity and brain health. Nature Reviews Neuroscience, 19, 63–80.
- Mehta, N. D., Stevens, J. S., Li, Z., Gillespie, C. F., Fani, N., Michopoulos, V., & Felger, J. C. (2020). Inflammation, reward circuitry and symptoms of anhedonia and PTSD in trauma-exposed women. Social Cognitive and Affective Neuroscience, 1046–1055. https://doi.org/10.1093/scan/nsz100
- Moro, T., Tinsley, G., Longo, G., Grigoletto, D., Bianco, A., Ferraris, C., Guglielmetti, M., Veneto, A., Tagliabue, A., Marcolin, G., & Paoli, A. (n.d.). Time-restricted eating effects on performance, immune function, and body composition in elite cyclists: A randomized controlled trial.
- Müller, F., Zaczek, H., Becker, A. M., et al. (n.d.). Efficacy and safety of low- versus high-dose LSD-assisted therapy in patients with major depression: A randomized trial.
- Murray, C. H. (2024). Common side effects of MDMA-assisted psychotherapy. Neuropsychopharmacology, 49, 1206–1207. https://doi.org/10.1038/s41386-024-01873-8
- Ommati, M. M., Mobasheri, A., Niknahad, H., Rezaei, M., Alidaee, S., Arjmand, A., Mazloomi, S., Abdoli, N., Sadeghian, I., Sabouri, S., Saeed, M., Mousavi, K., Najibi, A., & Heidari, R. (2023). Low-dose ketamine improves animals’ locomotor activity and decreases brain oxidative stress and inflammation in ammonia-induced neurotoxicity.
- Ornish, D., et al. (2024). Effects of intensive lifestyle changes on the progression of mild cognitive impairment or early dementia due to Alzheimer’s disease: A randomized, controlled clinical trial. Alzheimer’s Research & Therapy, 16, 122. https://doi.org/10.1186/s13195-024-01482-z
- P, S., & Vellapandian, C. (2024). Hypothalamic-pituitary-adrenal (HPA) axis: Unveiling the potential mechanisms involved in stress-induced Alzheimer’s disease and depression. Cureus, 16. https://doi.org/10.7759/cureus.67595
- Sällström, et al. (2025). Inflammatory response to red meats. BMC Nutrition, 11, 74. https://doi.org/10.1186/s40795-025-01055-9
- Selye, H. (1975). The stress of life.
- Solmi, M., Chen, C., Daure, C., Buot, A., Ljuslin, M., Verroust, V., Mallet, L., Khazaal, Y., Rothen, S., Thorens, G., Zullino, D., Gobbi, G., Rosenblat, J., Husain, M. I., De Gregorio, D., Castle, D., & Sabé, M. (2022). A century of research on psychedelics: A scientometric analysis on trends and knowledge maps of hallucinogens, entactogens, entheogens and dissociative drugs. European Neuropsychopharmacology, 64, 44–60.
- Vinyes, D., Muñoz-Sellart, M., & Fischer, L. (2023). Therapeutic use of low-dose local anesthetics in pain, inflammation, and other clinical conditions: A systematic scoping review. Journal of Clinical Medicine, 12, 7221. https://doi.org/10.3390/jcm12237221
- Wardill, H. R., da Silva Ferreira, A. R., Lichtenberg Cloo, S., Havinga, R., Harmsen, H. J. M., Vermeij, W. P., & Tissing, W. J. E. (n.d.). Pre-therapy fasting slows epithelial turnover and modulates the microbiota but fails to mitigate methotrexate-induced gastrointestinal mucositis.
- Wiciński, M., Fajkiel-Madajczyk, A., Kurant, Z., Kurant, D., Gryczka, K., Falkowski, M., Wiśniewska, M., Słupski, M., Ohla, J., & Zabrzyński, J. (2023). Can ashwagandha benefit the endocrine system?—A review. International Journal of Molecular Sciences, 24, 16513. https://doi.org/10.3390/ijms242216513
- Zorn, S., Ehret, J., Schäuble, R., Rautenberg, B., Ihorst, G., Bertz, H., Urbain, P., & Raynor, A. (n.d.). Impact of modified short-term fasting and its combination with a fasting supportive diet during chemotherapy on the incidence and severity of chemotherapy-induced toxicities in cancer patients: A controlled cross-over pilot study.
- Is microdosing a placebo? (2024). Journal of Psychopharmacology, 38(8), 701–711. https://doi.org/10.1177/02698811241254831
- The need for upper limits in physical activity guidelines: A narrative review. (n.d.).
- Ketogenic diet: A nutritional therapeutic tool for lipedema. (n.d.).
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